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<a href=https://tamoxifenolvadex.com/>side effects of tamoxifen</a> 1 Alcoholism Heavy alcohol use can cause elevated lactic acid levels Theoretically, heavy alcohol use combined with metformin could increase the risk of lactic acidosis 1 Advanced age As people age, their kidney function naturally declines The prescribing guidelines for metformin recommend that patients 80 years old have their kidney function monitored frequently and that metformin not be used at its maximum dose 1 DRUG INTERACTIONS NOTE The drug interactions presented here are NOT all-inclusive.